Asymmetric Total Synthesis of Brasilicardins
نویسندگان
چکیده
منابع مشابه
Asymmetric total synthesis of (+)-swainsonine.
A concise asymmetric synthesis of (+)-swainsonine (ent-1) is described starting from 2, which was readily prepared from commercially available l-glutamic acid. The method features installation of the indolizidine ring via an intramolecular cyclisation of α-sulfinyl carbanion as a key step. (+)-Swainsonine was obtained in 11.8% overall yield in 10 steps.
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2018
ISSN: 1433-7851,1521-3773
DOI: 10.1002/anie.201811403